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Genome Editing

The Indiana University Genome Editing Center at Indiana University School of Medicine is an institutionally subsidized shared resource whose mission is to provide Indiana University and external investigators access to state-of-the-art genome editing technologies by assisting with the generation of genetically modified organisms in a time- and cost-effective manner. The center exploits various technologies, including CRISPR-based genome editing systems, conventional gene targeting in embryonic stem cells and transgenesis, to engineer genetically modified transformed cell lines, stem cells and animals that will help identify and validate novel therapeutic targets, accelerate translational research, and advance precision medicine.

The Genome Editing Center was established  in July 2020 and is located in the Medical Library and Research Building room IB237, IB237A/B, IB250 and LARC. The center is outfitted with state-of-the-art molecular biology, cell biology, biochemistry, tissue culture, microinjection, surgery, and cryopreservation equipment.

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49 model generation services completed
98 traditional transgenic services completed
>400 cryopreserved models
Est. July 2020

Since inception of the core in July 2020.