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Expertise in Alzheimer's Disease

Basic and Preclinical Science

Basic scientists at Indiana University School of Medicine conduct leading-edge research on the neurobiology and molecular genetics of Alzheimer’s disease to define disease mechanisms using animal models, identify therapeutic targets, rigorously test drugs using preclinical testing protocols, and create molecules for potential drugs.

Researchers span many departments at IU School of Medicine and many collaborate on their investigations and grant-funded research through the Stark Neurosciences Research Institute. Model Organism Development and Evaluation for Late-Onset Alzheimer’s Disease (MODEL-AD) and the Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) work in tandem to advance discoveries in Alzheimer's research. The two National Institutes of Health funded grant programs are among the largest federally-funded studies at IU.

MODEL-AD researchers


The MODEL-AD consortium develops better animal models used by scientists throughout the United States to study contributors to Alzheimer’s disease and test potential treatments.
Learn More MODEL-AD


Researchers in TREAT-AD search for new therapeutic targets and molecules to accelerate the development of promising new drugs for Alzheimer’s disease at IU School of Medicine and other research institutions.
Learn More TREAT-AD

Interview an Alzheimer's Disease Expert

Schedule an interview with an IU School of Medicine faculty member or request materials and resources about Alzheimer’s disease research by contacting the IU School of Medicine media relations team.

Contact Media Relations