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Publications

Peer reviewed publications resulting from Indiana Center for Biological Microscopy resources are listed by year below. Papers in which images acquired either contributed to the body of the work or appeared as part of the published paper are shown.

  • 2022
    1. Behrouzi, A.;  Xia, H.;  Thompson, E. L.;  Kelley, M. R.; Fehrenbacher, J. C., Oxidative DNA Damage and Cisplatin Neurotoxicity Is Exacerbated by Inhibition of OGG1 Glycosylase Activity and APE1 Endonuclease Activity in Sensory Neurons. Int J Mol Sci 2022, 23 (3).

    2. Bhamidipati, T.;  Kumar, M.;  Verma, S. S.;  Mohanty, S. K.;  Kacar, S.;  Reese, D.;  Martinez, M. M.;  Kamocka, M. M.;  Dunn, K. W.;  Sen, C. K.; Singh, K., Epigenetic basis of diabetic vasculopathy. Front Endocrinol (Lausanne) 2022, 13, 989844.

    3. Canela, V. H.;  Bledsoe, S. B.;  Worcester, E. M.;  Lingeman, J. E.;  El-Achkar, T. M.; Williams, J. C., Jr., Collagen fibrils and cell nuclei are entrapped within Randall's plaques but not in CaOx matrix overgrowth: A microscopic inquiry into Randall's plaque stone pathogenesis. Anat Rec (Hoboken) 2022, 305 (7), 1701-1711.

    4. Canela, V. H.;  Dzien, C.;  Bledsoe, S. B.;  Borofsky, M. S.;  Boris, R. S.;  Lingeman, J. E.;  El-Achkar, T. M.; Williams, J. C., Jr., Human jackstone arms show a protein-rich, X-ray lucent core, suggesting that proteins drive their rapid and linear growth. Urolithiasis 2022, 50 (1), 21-28.

    5. Cokic, I.;  Chan, S. F.;  Guan, X.;  Nair, A. R.;  Yang, H. J.;  Liu, T.;  Chen, Y.;  Hernando, D.;  Sykes, J.;  Tang, R.;  Butler, J.;  Dohnalkova, A.;  Kovarik, L.;  Finney, R.;  Kali, A.;  Sharif, B.;  Bouchard, L. S.;  Gupta, R.;  Krishnam, M. S.;  Vora, K.;  Tamarappoo, B.;  Howarth, A. G.;  Kumar, A.;  Francis, J.;  Reeder, S. B.;  Wood, J. C.;  Prato, F. S.; Dharmakumar, R., Intramyocardial hemorrhage drives fatty degeneration of infarcted myocardium. Nat Commun 2022, 13 (1), 6394.

    6. Collins, K. S.;  Eadon, M. T.;  Cheng, Y. H.;  Barwinska, D.;  Melo Ferreira, R.;  McCarthy, T. W.;  Janosevic, D.;  Syed, F.;  Maier, B.;  El-Achkar, T. M.;  Kelly, K. J.;  Phillips, C. L.;  Hato, T.;  Sutton, T. A.; Dagher, P. C., Alterations in Protein Translation and Carboxylic Acid Catabolic Processes in Diabetic Kidney Disease. Cells 2022, 11 (7).

    7. Dunn, K. W.;  Hall, A. M.; Molitoris, B. A., Editorial: Proceedings of the 2021 Indiana O'Brien Center Microscopy Workshop. Front Physiol 2022, 13, 891526.

    8. Eadon, M. T.;  Dagher, P. C.; El-Achkar, T. M., Cellular and molecular interrogation of kidney biopsy specimens. Curr Opin Nephrol Hypertens 2022, 31 (2), 160-167.

    9. El-Achkar, T. M.;  Winfree, S.;  Talukder, N.;  Barwinska, D.;  Ferkowicz, M. J.; Al Hasan, M., Tissue Cytometry With Machine Learning in Kidney: From Small Specimens to Big Data. Front Physiol 2022, 13, 832457.

    10. George, R. M.;  Guo, S.;  Firulli, B. A.;  Rubart, M.; Firulli, A. B., Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis. J Cardiovasc Dev Dis 2022, 9 (7).

    11. Hansen, J.;  Sealfon, R.;  Menon, R.;  Eadon, M. T.;  Lake, B. B.;  Steck, B.;  Anjani, K.;  Parikh, S.;  Sigdel, T. K.;  Zhang, G.;  Velickovic, D.;  Barwinska, D.;  Alexandrov, T.;  Dobi, D.;  Rashmi, P.;  Otto, E. A.;  Rivera, M.;  Rose, M. P.;  Anderton, C. R.;  Shapiro, J. P.;  Pamreddy, A.;  Winfree, S.;  Xiong, Y.;  He, Y.;  de Boer, I. H.;  Hodgin, J. B.;  Barisoni, L.;  Naik, A. S.;  Sharma, K.;  Sarwal, M. M.;  Zhang, K.;  Himmelfarb, J.;  Rovin, B.;  El-Achkar, T. M.;  Laszik, Z.;  He, J. C.;  Dagher, P. C.;  Valerius, M. T.;  Jain, S.;  Satlin, L. M.;  Troyanskaya, O. G.;  Kretzler, M.;  Iyengar, R.; Azeloglu, E. U., A reference tissue atlas for the human kidney. Sci Adv 2022, 8 (23), eabn4965.

    12. Jones, N. M.;  Sysol, J. R.;  Singla, S.;  Smith, P.;  Sandusky, G. E.;  Wang, H.;  Natarajan, V.;  Dudek, S. M.; Machado, R. F., Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease. Am J Physiol Lung Cell Mol Physiol 2022, 322 (6), L890-l897.

    13. Jose, L.;  Androphy, E. J.; DeSmet, M., SETD6 Regulates E2-Dependent Human Papillomavirus Transcription. J Virol 2022, 96 (22), e0129522.

    14. Joshi, J.;  Xu, B.;  Rubart, M.;  Chang, Y.;  Bao, X.;  Chaliki, H. P.;  Scott, L. R.; Zhu, W., Optogenetic Control of Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Live Mice: A Proof-of-Concept Study. Cells 2022, 11 (6).

    15. Kanginakudru, S.;  Gilson, T.;  Jose, L.; Androphy, E. J., Effects of Caffeine, a DNA Damage Response Inhibitor, on Papillomavirus Genome Replication. Pathogens 2022, 11 (11).

    16. LaFavers, K. A.; El-Achkar, T. M., Systemic Effects of Tamm-Horsfall Protein in Kidney Disease. Semin Nephrol 2022, 42 (3), 151277.

    17. LaFavers, K. A.;  Hage, C. A.;  Gaur, V.;  Micanovic, R.;  Hato, T.;  Khan, S.;  Winfree, S.;  Doshi, S.;  Moorthi, R. N.;  Twigg, H.;  Wu, X. R.;  Dagher, P. C.;  Srour, E. F.; El-Achkar, T. M., The kidney protects against sepsis by producing systemic uromodulin. Am J Physiol Renal Physiol 2022, 323 (2), F212-f226.

    18. LaFavers, K. A.;  Micanovic, R.;  Sabo, A. R.;  Maghak, L. A.; El-Achkar, T. M., Evolving Concepts in Uromodulin Biology, Physiology, and Its Role in Disease: a Tale of Two Forms. Hypertension 2022, 79 (11), 2409-2418.

    19. Liu, J.;  Nair, V.;  Zhao, Y. Y.;  Chang, D. Y.;  Limonte, C.;  Bansal, N.;  Fermin, D.;  Eichinger, F.;  Tanner, E. C.;  Bellovich, K. A.;  Steigerwalt, S.;  Bhat, Z.;  Hawkins, J. J.;  Subramanian, L.;  Rosas, S. E.;  Sedor, J. R.;  Vasquez, M. A.;  Waikar, S. S.;  Bitzer, M.;  Pennathur, S.;  Brosius, F. C.;  De Boer, I.;  Chen, M.;  Kretzler, M.; Ju, W., Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease. Diabetes 2022, 71 (12), 2664-2676.

    20. Lutnick, B.;  Manthey, D.;  Becker, J. U.;  Ginley, B.;  Moos, K.;  Zuckerman, J. E.;  Rodrigues, L.;  Gallan, A. J.;  Barisoni, L.;  Alpers, C. E.;  Wang, X. X.;  Myakala, K.;  Jones, B. A.;  Levi, M.;  Kopp, J. B.;  Yoshida, T.;  Zee, J.;  Han, S. S.;  Jain, S.;  Rosenberg, A. Z.;  Jen, K. Y.; Sarder, P., A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology. Commun Med (Lond) 2022, 2, 105.

    21. Melo Ferreira, R.;  Gisch, D. L.; Eadon, M. T., Spatial transcriptomics and the kidney. Curr Opin Nephrol Hypertens 2022, 31 (3), 244-250.

    22. Menon, R.;  Bomback, A. S.;  Lake, B. B.;  Stutzke, C.;  Grewenow, S. M.;  Menez, S.;  D'Agati, V. D.; Jain, S., Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation. Kidney Int 2022, 101 (6), 1116-1125.

    23. Micanovic, R.;  LaFavers, K. A.;  Patidar, K. R.;  Ghabril, M. S.;  Doud, E. H.;  Mosley, A. L.;  Sabo, A. R.;  Khan, S.; El-Achkar, T. M., The kidney releases a nonpolymerizing form of uromodulin in the urine and circulation that retains the external hydrophobic patch domain. Am J Physiol Renal Physiol 2022, 322 (4), F403-f418.

    24. Molitoris, B. A.;  Sandoval, R. M.; Wagner, M. C., Intravital Multiphoton Microscopy as a Tool for Studying Renal Physiology, Pathophysiology and Therapeutics. Front Physiol 2022, 13, 827280.

    25. Molitoris, B. A.;  Sandoval, R. M.;  Yadav, S. P. S.; Wagner, M. C., Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiol Rev 2022, 102 (4), 1625-1667.

    26. Mulcrone, P. L.;  Zhang, J.;  Pride, P. M.;  Lam, A. K.;  Frabutt, D. A.;  Ball-Kell, S. M.; Xiao, W., Genomic Designs of rAAVs Contribute to Pathological Changes in the Livers and Spleens of Mice. Adv Cell Gene Ther 2022, 2022.

    27. Nie, J.;  Ueda, Y.;  Solivais, A. J.; Hashino, E., CHD7 regulates otic lineage specification and hair cell differentiation in human inner ear organoids. Nat Commun 2022, 13 (1), 7053.

    28. Noori-Dokht, H.;  Joukar, A.;  Karnik, S.;  Williams, T.;  Trippel, S. B.; Wagner, D. R., A Photochemical Crosslinking Approach to Enhance Resistance to Mechanical Wear and Biochemical Degradation of Articular Cartilage. Cartilage 2022, 13 (3), 19476035221093064.

    29. Panariello, B. H. D.;  Cavichioli, E. A. M.;  Sochacki, S. F.;  Gandini Junior, L. G.; Duarte, S., Effect of blue light plus chlorhexidine therapy on Streptococcus mutans biofilm and its regrowth in an in vitro orthodontic model. Am J Orthod Dentofacial Orthop 2022, 161 (1), 103-114.

    30. Rosin, D. L.;  Hall, J. P.;  Zheng, S.;  Huang, L.;  Campos-Bilderback, S.;  Sandoval, R.;  Bree, A.;  Beaumont, K.;  Miller, E.;  Larsen, J.;  Hariri, G.;  Kaila, N.;  Encarnacion, I. M.;  Gale, J. D.;  van Elsas, A.;  Molitoris, B. A.; Okusa, M. D., Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors. Front Med (Lausanne) 2022, 9, 931293.

    31. Sabo, A. R.;  Winfree, S.;  Bledsoe, S. B.;  Phillips, C. L.;  Lingeman, J. E.;  Eadon, M. T.;  Williams, J. C., Jr.; El-Achkar, T. M., Label-free imaging of non-deparaffinized sections of the human kidney to determine tissue quality and signatures of disease. Physiol Rep 2022, 10 (3), e15167.

    32. Saxena, V.;  Arregui, S.;  Kamocka, M. M.;  Hains, D. S.; Schwaderer, A., MAP3K7 is an innate immune regulatory gene with increased expression in human and murine kidney intercalated cells following uropathogenic Escherichia coli exposure. J Cell Biochem 2022, 123 (11), 1817-1826.

    33. So, J.;  Taleb, S.;  Wann, J.;  Strobel, O.;  Kim, K.; Roh, H. C., Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibility. Mol Metab 2022, 66, 101619.

    34. Tonon, C. C.;  Panariello, B.;  Chorilli, M.;  Spolidorio, D. M. P.; Duarte, S., Effect of curcumin-loaded photoactivatable polymeric nanoparticle on peri-implantitis-related biofilm. Photodiagnosis Photodyn Ther 2022, 40, 103150.

    35. Ueda, Y.;  Moore, S. T.; Hashino, E., Directed Differentiation of Human Pluripotent Stem Cells into Inner Ear Organoids. Methods Mol Biol 2022, 2520, 135-150.

    36. Ueoka, A.;  Sung, Y. L.;  Liu, X.;  Rosenberg, C.;  Chen, Z.;  Everett, T. H. t.;  Rubart, M.;  Tisdale, J. E.; Chen, P. S., Testosterone does not shorten action potential duration in Langendorff-perfused rabbit ventricles. Heart Rhythm 2022.

    37. Wagner, L. E.;  Melnyk, O.;  Duffett, B. E.; Linnemann, A. K., Mouse models and human islet transplantation sites for intravital imaging. Front Endocrinol (Lausanne) 2022, 13, 992540.

    38. Wagner, M. C.;  Sandoval, R. M.;  Campos-Bilderback, S. B.; Molitoris, B. A., Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes. J Vis Exp 2022,  (181).

    39. Williams, J. C., Jr.;  Al-Awadi, H.;  Muthenini, M.;  Bledsoe, S. B.;  El-Achkar, T.;  Evan, A. P.;  Coe, F.;  Lingeman, J. E.; Worcester, E. M., Stone Morphology Distinguishes Two Pathways of Idiopathic Calcium Oxalate Stone Pathogenesis. J Endourol 2022, 36 (5), 694-702.

    40. Winfree, S.;  Al Hasan, M.; El-Achkar, T. M., Profiling Immune Cells in the Kidney Using Tissue Cytometry and Machine Learning. Kidney360 2022, 3 (5), 968-978.

  • 2021
    1. Barwinska, D.;  El-Achkar, T. M.;  Melo Ferreira, R.;  Syed, F.;  Cheng, Y. H.;  Winfree, S.;  Ferkowicz, M. J.;  Hato, T.;  Collins, K. S.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Rovin, B. H.;  Parikh, S. V.;  Phillips, C. L.;  Dagher, P. C.; Eadon, M. T., Molecular characterization of the human kidney interstitium in health and disease. Sci Adv 2021, 7 (7).

    2. Bellchambers, H. M.; Ware, S. M., Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects. Hum Mol Genet 2021, 30 (24), 2402-2415.

    3. Black, L. M.;  Farrell, E. R.;  Barwinska, D.;  Osis, G.;  Zmijewska, A. A.;  Traylor, A. M.;  Esman, S. K.;  Bolisetty, S.;  Whipple, G.;  Kamocka, M. M.;  Winfree, S.;  Spangler, D. R.;  Khan, S.;  Zarjou, A.;  El-Achkar, T. M.; Agarwal, A., VEGFR3 tyrosine kinase inhibition aggravates cisplatin nephrotoxicity. Am J Physiol Renal Physiol 2021, 321 (6), F675-f688.

    4. Black, L. M.;  Winfree, S.;  Khochare, S. D.;  Kamocka, M. M.;  Traylor, A. M.;  Esman, S. K.;  Khan, S.;  Zarjou, A.;  Agarwal, A.; El-Achkar, T. M., Quantitative 3-dimensional imaging and tissue cytometry reveals lymphatic expansion in acute kidney injury. Lab Invest 2021, 101 (9), 1186-1196.

    5. Canela, V. H.;  Bledsoe, S. B.;  Lingeman, J. E.;  Gerber, G.;  Worcester, E. M.;  El-Achkar, T. M.; Williams, J. C., Jr., Demineralization and sectioning of human kidney stones: A molecular investigation revealing the spatial heterogeneity of the stone matrix. Physiol Rep 2021, 9 (1), e14658.

    6. Canela, V. H.;  Bledsoe, S. B.;  Worcester, E. M.;  Lingeman, J. E.;  El-Achkar, T. M.; Williams, J. C., Jr., Collagen fibrils and cell nuclei are entrapped within Randall's plaques but not in CaOx matrix overgrowth: A microscopic inquiry into Randall's plaque stone pathogenesis. Anat Rec (Hoboken) 2021.

    7. Chen, N. X.;  O'Neill, K. D.;  Dominguez, J. M., 2nd; Moe, S. M., Regulation of reactive oxygen species in the pathogenesis of matrix vesicles induced calcification of recipient vascular smooth muscle cells. Vasc Med 2021, 26 (6), 585-594.

    8. Dunn, K. W., Digital Image Analysis Tools Developed by the Indiana O'Brien Center. Front Physiol 2021, 12, 812170.

    9. Dunn, K. W.;  Molitoris, B. A.; Dagher, P. C., The Indiana O'Brien Center for Advanced Renal Microscopic Analysis. Am J Physiol Renal Physiol 2021, 320 (5), F671-f682.

    10. Eadon, M. T.;  Lampe, S.;  Baig, M. M.;  Collins, K. S.;  Melo Ferreira, R.;  Mang, H.;  Cheng, Y. H.;  Barwinska, D.;  El-Achkar, T. M.;  Schwantes-An, T. H.;  Winfree, S.;  Temm, C. J.;  Ferkowicz, M. J.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Moe, S. M.;  Moorthi, R. N.;  Phillips, C. L.; Dagher, P. C., Clinical, histopathologic and molecular features of idiopathic and diabetic nodular mesangial sclerosis in humans. Nephrol Dial Transplant 2021, 37 (1), 72-84.

    11. El-Achkar, T. M.;  Eadon, M. T.;  Menon, R.;  Lake, B. B.;  Sigdel, T. K.;  Alexandrov, T.;  Parikh, S.;  Zhang, G.;  Dobi, D.;  Dunn, K. W.;  Otto, E. A.;  Anderton, C. R.;  Carson, J. M.;  Luo, J.;  Park, C.;  Hamidi, H.;  Zhou, J.;  Hoover, P.;  Schroeder, A.;  Joanes, M.;  Azeloglu, E. U.;  Sealfon, R.;  Winfree, S.;  Steck, B.;  He, Y.;  D'Agati, V.;  Iyengar, R.;  Troyanskaya, O. G.;  Barisoni, L.;  Gaut, J.;  Zhang, K.;  Laszik, Z.;  Rovin, B. H.;  Dagher, P. C.;  Sharma, K.;  Sarwal, M. M.;  Hodgin, J. B.;  Alpers, C. E.;  Kretzler, M.; Jain, S., A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics 2021, 53 (1), 1-11.

    12. Fang, Y.;  Wang, L.;  Wan, C.;  Sun, Y.;  Van der Jeught, K.;  Zhou, Z.;  Dong, T.;  So, K. M.;  Yu, T.;  Li, Y.;  Eyvani, H.;  Colter, A. B.;  Dong, E.;  Cao, S.;  Wang, J.;  Schneider, B. P.;  Sandusky, G. E.;  Liu, Y.;  Zhang, C.;  Lu, X.; Zhang, X., MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation. J Clin Invest 2021, 131 (1).

    13. Ferkowicz, M. J.;  Winfree, S.;  Sabo, A. R.;  Kamocka, M. M.;  Khochare, S.;  Barwinska, D.;  Eadon, M. T.;  Cheng, Y. H.;  Phillips, C. L.;  Sutton, T. A.;  Kelly, K. J.;  Dagher, P. C.;  El-Achkar, T. M.; Dunn, K. W., Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. Lab Invest 2021, 101 (5), 661-676.

    14. Garcia, B. A.;  Panariello, B. H. D.;  Freitas-Pontes, K. M.; Duarte, S., Candida biofilm matrix as a resistance mechanism against photodynamic therapy. Photodiagnosis Photodyn Ther 2021, 36, 102525.

    15. Janosevic, D.;  Myslinski, J.;  McCarthy, T. W.;  Zollman, A.;  Syed, F.;  Xuei, X.;  Gao, H.;  Liu, Y. L.;  Collins, K. S.;  Cheng, Y. H.;  Winfree, S.;  El-Achkar, T. M.;  Maier, B.;  Melo Ferreira, R.;  Eadon, M. T.;  Hato, T.; Dagher, P. C., The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline. Elife 2021, 10.

    16. Melo Ferreira, R.;  Sabo, A. R.;  Winfree, S.;  Collins, K. S.;  Janosevic, D.;  Gulbronson, C. J.;  Cheng, Y. H.;  Casbon, L.;  Barwinska, D.;  Ferkowicz, M. J.;  Xuei, X.;  Zhang, C.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Hato, T.;  Dagher, P. C.;  El-Achkar, T. M.; Eadon, M. T., Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury. JCI Insight 2021, 6 (12).

    17. Miller, S. G.;  Hafen, P. S.;  Law, A. S.;  Springer, C. B.;  Logsdon, D. L.;  O'Connell, T. M.;  Witczak, C. A.; Brault, J. J., AMP deamination is sufficient to replicate an atrophy-like metabolic phenotype in skeletal muscle. Metabolism 2021, 123, 154864.

    18. Panariello, B. H. D.;  Kindler, J. K.;  Spolnik, K. J.;  Ehrlich, Y.;  Eckert, G. J.; Duarte, S., Use of electromagnetic stimulation on an Enterococcus faecalis biofilm on root canal treated teeth in vitro. Sci Rep 2021, 11 (1), 8306.

    19. Ruan, J.;  Zhang, L.;  Hu, D.;  Qu, X.;  Yang, F.;  Chen, F.;  He, X.;  Shen, J.;  Dong, K.;  Sweet, M.;  Sanchez, C.;  Li, D.;  Shou, W.;  Zhou, J.; Cai, C. L., Novel Myh11 Dual Reporter Mouse Model Provides Definitive Labeling and Identification of Smooth Muscle Cells-Brief Report. Arterioscler Thromb Vasc Biol 2021, 41 (2), 815-821.

    20. Saxena, V.;  Gao, H.;  Arregui, S.;  Zollman, A.;  Kamocka, M. M.;  Xuei, X.;  McGuire, P.;  Hutchens, M.;  Hato, T.;  Hains, D. S.; Schwaderer, A. L., Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli. Nat Commun 2021, 12 (1), 2405.

    21. Tonon, C. C.;  Panariello, B. H. D.;  Spolidorio, D. M. P.;  Gossweiler, A. G.; Duarte, S., Antibiofilm effect of ozonized physiological saline solution on peri-implant-related biofilm. J Periodontol 2021, 92 (8), 1151-1162.

    22. Ueda, Y.;  Moore, S. T.; Hashino, E., Directed Differentiation of Human Pluripotent Stem Cells into Inner Ear Organoids. Methods Mol Biol 2021.

    23. Winfree, S.;  Weiler, C.;  Bledsoe, S. B.;  Gardner, T.;  Sommer, A. J.;  Evan, A. P.;  Lingeman, J. E.;  Krambeck, A. E.;  Worcester, E. M.;  El-Achkar, T. M.; Williams, J. C., Jr., Multimodal imaging reveals a unique autofluorescence signature of Randall's plaque. Urolithiasis 2021, 49 (2), 123-135.

    24. Woloshuk, A.;  Khochare, S.;  Almulhim, A. F.;  McNutt, A. T.;  Dean, D.;  Barwinska, D.;  Ferkowicz, M. J.;  Eadon, M. T.;  Kelly, K. J.;  Dunn, K. W.;  Hasan, M. A.;  El-Achkar, T. M.; Winfree, S., In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining. Cytometry A 2021, 99 (7), 707-721.

    25. Xu, H.;  Van der Jeught, K.;  Zhou, Z.;  Zhang, L.;  Yu, T.;  Sun, Y.;  Li, Y.;  Wan, C.;  So, K. M.;  Liu, D.;  Frieden, M.;  Fang, Y.;  Mosley, A. L.;  He, X.;  Zhang, X.;  Sandusky, G. E.;  Liu, Y.;  Meroueh, S. O.;  Zhang, C.;  Wijeratne, A. B.;  Huang, C.;  Ji, G.; Lu, X., Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation. J Clin Invest 2021, 131 (10).

    26. Yadav, S. P. S.;  Sandoval, R. M.;  Zhao, J.;  Huang, Y.;  Wang, E.;  Kumar, S.;  Campos-Bilderback, S. B.;  Rhodes, G.;  Mechref, Y.;  Molitoris, B. A.; Wagner, M. C., Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol 2021, 320 (1), F114-f129.

  • 2020
    1. Adhyapok, P.;  Fu, X.;  Sluka, J. P.;  Clendenon, S. G.;  Sluka, V. D.;  Wang, Z.;  Dunn, K.;  Klaunig, J. E.; Glazier, J. A., A computational model of liver tissue damage and repair. PLoS One 2020, 15 (12), e0243451. 

    2. Barwinska, D.;  Ferkowicz, M. J.;  Cheng, Y. H.;  Winfree, S.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Rovin, B. H.;  Parikh, S. V.;  Phillips, C. L.;  Dagher, P. C.;  El-Achkar, T. M.; Eadon, M. T., Application of Laser Microdissection to Uncover Regional Transcriptomics in Human Kidney Tissue. J Vis Exp 2020,  (160). 

    3. Chen, N. X.;  Srinivasan, S.;  O'Neill, K.;  Nickolas, T. L.;  Wallace, J. M.;  Allen, M. R.;  Metzger, C. E.;  Creecy, A.;  Avin, K. G.; Moe, S. M., Effect of Advanced Glycation End-Products (AGE) Lowering Drug ALT-711 on Biochemical, Vascular, and Bone Parameters in a Rat Model of CKD-MBD. J Bone Miner Res 2020, 35 (3), 608-617. 

    4. Dunn, K. W.;  Martinez, M. M.;  Wang, Z.;  Mang, H. E.;  Clendenon, S. G.;  Sluka, J. P.;  Glazier, J. A.; Klaunig, J. E., Mitochondrial depolarization and repolarization in the early stages of acetaminophen hepatotoxicity in mice. Toxicology 2020, 439, 152464. 

    5. Durbin, M. D.;  O'Kane, J.;  Lorentz, S.;  Firulli, A. B.; Ware, S. M., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol 2020, 464 (2), 124-136. 

    6. Elbanna, M.;  Orillion, A. R.;  Damayanti, N. P.;  Adelaiye-Ogala, R.;  Shen, L.;  Miles, K. M.;  Chintala, S.;  Ciamporcero, E.;  Ramakrishnan, S.;  Ku, S. Y.;  Rex, K.;  Caenepeel, S.;  Coxon, A.; Pili, R., Dual Inhibition of Angiopoietin-TIE2 and MET Alters the Tumor Microenvironment and Prolongs Survival in a Metastatic Model of Renal Cell Carcinoma. Mol Cancer Ther 2020, 19 (1), 147-156. 

    7. Firulli, B. A.;  George, R. M.;  Harkin, J.;  Toolan, K. P.;  Gao, H.;  Liu, Y.;  Zhang, W.;  Field, L. J.;  Liu, Y.;  Shou, W.;  Payne, R. M.;  Rubart-von der Lohe, M.; Firulli, A. B., HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. Cardiovasc Res 2020, 116 (3), 605-618. 

    8. Garcia, B. A.;  Panariello, B. H. D.;  de Freitas Pontes, K. M.; Duarte, S., Regimen and different surfaces interfere with photodynamic therapy on Candida albicans biofilms. J Microbiol Methods 2020, 178, 106080. 

    9. Ho, D. J.;  Mas Montserrat, D.;  Fu, C.;  Salama, P.;  Dunn, K. W.; Delp, E. J., Sphere estimation network: three-dimensional nuclei detection of fluorescence microscopy images. J Med Imaging (Bellingham) 2020, 7 (4), 044003. 

    10. Hossain, M. J.;  Noori-Dokht, H.;  Karnik, S.;  Alyafei, N.;  Joukar, A.;  Trippel, S. B.; Wagner, D. R., Anisotropic properties of articular cartilage in an accelerated in vitro wear test. J Mech Behav Biomed Mater 2020, 109, 103834. 

    11. Lee, J.;  Rabbani, C. C.;  Gao, H.;  Steinhart, M. R.;  Woodruff, B. M.;  Pflum, Z. E.;  Kim, A.;  Heller, S.;  Liu, Y.;  Shipchandler, T. Z.; Koehler, K. R., Hair-bearing human skin generated entirely from pluripotent stem cells. Nature 2020, 582 (7812), 399-404. 

    12. Liu, X. F.;  Wei, J.;  Zhou, Q.;  Molitoris, B. A.;  Sandoval, R.;  Kobayashi, H.;  Okada, R.;  Nagaya, T.;  Karim, B.;  Butcher, D.; Pastan, I., Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A 2020, 117 (11), 6086-6091. 

    13. Madhivanan, K.;  Ramadesikan, S.;  Hsieh, W. C.;  Aguilar, M. C.;  Hanna, C. B.;  Bacallao, R. L.; Aguilar, R. C., Lowe syndrome patient cells display mTOR- and RhoGTPase-dependent phenotypes alleviated by rapamycin and statins. Hum Mol Genet 2020, 29 (10), 1700-1715. 

    14. Makki, M. S.;  Winfree, S.;  Lingeman, J. E.;  Witzmann, F. A.;  Worcester, E. M.;  Krambeck, A. E.;  Coe, F. L.;  Evan, A. P.;  Bledsoe, S.;  Bergsland, K. J.;  Khochare, S.;  Barwinska, D.;  Williams, J. C., Jr.; El-Achkar, T. M., A Precision Medicine Approach Uncovers a Unique Signature of Neutrophils in Patients With Brushite Kidney Stones. Kidney Int Rep 2020, 5 (5), 663-677. 

    15. Matos, A. O.;  de Almeida, A. B.;  Beline, T.;  Tonon, C. C.;  Casarin, R. C. V.;  Windsor, L. J.;  Duarte, S.;  Nociti, F. H., Jr.;  Rangel, E. C.;  Gregory, R. L.; Barão, V. A. R., Synthesis of multifunctional chlorhexidine-doped thin films for titanium-based implant materials. Mater Sci Eng C Mater Biol Appl 2020, 117, 111289. 

    16. Micanovic, R.;  LaFavers, K.;  Garimella, P. S.;  Wu, X. R.; El-Achkar, T. M., Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrol Dial Transplant 2020, 35 (1), 33-43. 

    17. Miyagawa, K.;  Ohata, Y.;  Delgado-Calle, J.;  Teramachi, J.;  Zhou, H.;  Dempster, D. D.;  Subler, M. A.;  Windle, J. J.;  Chirgwin, J. M.;  Roodman, G. D.; Kurihara, N., Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo. JCI Insight 2020, 5 (6). 

    18. Mulcrone, P. L.;  Edwards, S. K. E.;  Petrusca, D. N.;  Haneline, L. S.;  Delgado-Calle, J.; Roodman, G. D., Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23. Sci Rep 2020, 10 (1), 17319. 

    19. Nie, J.; Hashino, E., Generation of inner ear organoids from human pluripotent stem cells. Methods Cell Biol 2020, 159, 303-321. 

    20. Reissaus, C. A.;  Day, K. H.;  Mirmira, R. G.;  Dunn, K. W.;  Pavalko, F. M.; Day, R. N., PIE-FLIM Measurements of Two Different FRET-Based Biosensor Activities in the Same Living Cells. Biophys J 2020, 118 (8), 1820-1829. 

    21. Tonon, C. C.;  Panariello, B. H. D.;  Spolidorio, D. M. P.;  Gossweiler, A. G.; Duarte, S., Anti-biofilm effect of ozonized physiological saline solution on peri-implant-related biofilm. J Periodontol 2020. 

    22. Van der Jeught, K.;  Sun, Y.;  Fang, Y.;  Zhou, Z.;  Jiang, H.;  Yu, T.;  Yang, J.;  Kamocka, M. M.;  So, K. M.;  Li, Y.;  Eyvani, H.;  Sandusky, G. E.;  Frieden, M.;  Braun, H.;  Beyaert, R.;  He, X.;  Zhang, X.;  Zhang, C.;  Paczesny, S.; Lu, X., ST2 as checkpoint target for colorectal cancer immunotherapy. JCI Insight 2020, 5 (9). 

    23. Woloshuk, A.;  Khochare, S.;  Almulhim, A. F.;  McNutt, A. T.;  Dean, D.;  Barwinska, D.;  Ferkowicz, M. J.;  Eadon, M. T.;  Kelly, K. J.;  Dunn, K. W.;  Hasan, M. A.;  El-Achkar, T. M.; Winfree, S., In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining. Cytometry A 2020. 

    24. Yi, X.;  Wright, L. E.;  Pagnotti, G. M.;  Uzer, G.;  Powell, K. M.;  Wallace, J. M.;  Sankar, U.;  Rubin, C. T.;  Mohammad, K.;  Guise, T. A.; Thompson, W. R., Mechanical suppression of breast cancer cell invasion and paracrine signaling to osteoclasts requires nucleo-cytoskeletal connectivity. Bone Res 2020, 8 (1), 40.

  • 2019

    1. Basile, D. P.; Yoder, M. C., Unique Gene Expression in Developing Ascending Vasa Recta: A Tale of Tie. Journal of the American Society of Nephrology : JASN 2018, 29 (4), 1073-1074.
    2. Burkhalter, M. D.;  Sridhar, A.;  Sampaio, P.;  Jacinto, R.;  Burczyk, M. S.;  Donow, C.;  Angenendt, M.;  Hempel, M.;  Walther, P.;  Pennekamp, P.;  Omran, H.;  Lopes, S. S.;  Ware, S. M.; Philipp, M., Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest 2019, 129 (7), 2841-2855.

    3. Clendenon, S. G.;  Fu, X.;  Von Hoene, R. A.;  Clendenon, J. L.;  Sluka, J. P.;  Winfree, S.;  Mang, H.;  Martinez, M.;  Filson, A.;  Klaunig, J. E.;  Glazier, J. A.; Dunn, K. W., Spatial Temporal Analysis of Fieldwise Flow in Microvasculature. J Vis Exp 2019,  (153).

    4. Clendenon, S. G.;  Fu, X.;  Von Hoene, R. A.;  Clendenon, J. L.;  Sluka, J. P.;  Winfree, S.;  Mang, H.;  Martinez, M.;  Filson, A. J.;  Klaunig, J. E.;  Glazier, J. A.; Dunn, K. W., A simple automated method for continuous fieldwise measurement of microvascular hemodynamics. Microvascular research 2019, 123, 7-13.

    5. Conteh, A. M.;  Reissaus, C. A.;  Hernandez-Perez, M.;  Nakshatri, S.;  Anderson, R. M.;  Mirmira, R. G.;  Tersey, S. A.; Linnemann, A. K., Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet beta cells. J Biol Chem 2019, 294 (16), 6612-6620.

    6. DeSmet, M.;  Jose, L.;  Isaq, N.; Androphy, E. J., Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication. J Virol 2019, 93 (10).

    7. Dunn, K. W.;  Fu, C.;  Ho, D. J.;  Lee, S.;  Han, S.;  Salama, P.; Delp, E. J., DeepSynth: Three-dimensional nuclear segmentation of biological images using neural networks trained with synthetic data. Sci Rep 2019, 9 (1), 18295.

    8. Ferrell, N.;  Sandoval, R. M.;  Molitoris, B. A.;  Brakeman, P.;  Roy, S.; Fissell, W. H., Application of physiological shear stress to renal tubular epithelial cells. Methods Cell Biol 2019, 153, 43-67.

    9. Firulli, B. A.;  George, R. M.;  Harkin, J.;  Toolan, K. P.;  Gao, H.;  Liu, Y.;  Zhang, W.;  Field, L. J.;  Liu, Y.;  Shou, W.;  Payne, R. M.;  Rubart-von der Lohe, M.; Firulli, A. B., HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. Cardiovasc Res 2020, 116 (3), 605-618.

    10. Gadgil, N. J.;  Salama, P.;  Dunn, K. W.; Delp, E. J., Segmentation of biological images containing multitarget labeling using the jelly filling framework. Journal of medical imaging (Bellingham, Wash.) 2018, 5 (4), 044006.

    11. Garrett, J.;  Sampson, C. H.;  Plett, P. A.;  Crisler, R.;  Parker, J.;  Venezia, R.;  Chua, H. L.;  Hickman, D. L.;  Booth, C.;  MacVittie, T.;  Orschell, C. M.; Dynlacht, J. R., Characterization and Etiology of Swollen Muzzles in Irradiated Mice. Radiation research 2019, 191 (1), 31-42.

    12. Hato, T.;  Maier, B.;  Syed, F.;  Myslinski, J.;  Zollman, A.;  Plotkin, Z.;  Eadon, M. T.; Dagher, P. C., Bacterial sepsis triggers an antiviral response that causes translation shutdown. J Clin Invest 2019, 129 (1), 296-309.

    13. Heredero-Bermejo, I.;  Varberg, J. M.;  Charvat, R.;  Jacobs, K.;  Garbuz, T.;  Sullivan, W. J., Jr.; Arrizabalaga, G., TgDrpC, an atypical dynamin-related protein in Toxoplasma gondii, is associated with vesicular transport factors and parasite division. Mol Microbiol 2019, 111 (1), 46-64.

    14. LaFavers, K. A.;  Macedo, E.;  Garimella, P. S.;  Lima, C.;  Khan, S.;  Myslinski, J.;  McClintick, J.;  Witzmann, F. A.;  Winfree, S.;  Phillips, C. L.;  Hato, T.;  Dagher, P. C.;  Wu, X. R.;  El-Achkar, T. M.; Micanovic, R., Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel. Sci Transl Med 2019, 11 (512).

    15. Lin, Y.;  Gil, C. H.; Yoder, M. C., Identification of Circulating Endothelial Colony-Forming Cells from Murine Embryonic Peripheral Blood. Methods in molecular biology (Clifton, N.J.) 2019, 1940, 97-107.

    16. Lin, Y.;  Kobayashi, M.;  Azevedo Portilho, N.;  Mishra, A.;  Gao, H.;  Liu, Y.;  Wenzel, P.;  Davis, B.;  Yoder, M. C.; Yoshimoto, M., Long-Term Engraftment of ESC-Derived B-1 Progenitor Cells Supports HSC-Independent Lymphopoiesis. Stem cell reports 2019, 12 (3), 572-583.

    17. Micanovic, R.;  LaFavers, K.;  Garimella, P. S.;  Wu, X. R.; El-Achkar, T. M., Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrol Dial Transplant 2020, 35 (1), 33-43.

    18. Micanovic, R.;  LaFavers, K.;  Garimella, P. S.;  Wu, X. R.; El-Achkar, T. M., Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2019.

    19. Motea, E. A.;  Huang, X.;  Singh, N.;  Kilgore, J. A.;  Williams, N. S.;  Xie, X. J.;  Gerber, D. E.;  Beg, M. S.;  Bey, E. A.; Boothman, D. A., NQO1-dependent, Tumor-selective Radiosensitization of Non-small Cell Lung Cancers. Clin Cancer Res 2019, 25 (8), 2601-2609.

    20. Ohlemacher, S. K.;  Langer, K. B.;  Fligor, C. M.;  Feder, E. M.;  Edler, M. C.; Meyer, J. S., Advances in the Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells. Adv Exp Med Biol 2019, 1186, 121-140.

    21. Pan, Z.;  Ai, T.;  Chang, P. C.;  Liu, Y.;  Liu, J.;  Maruyama, M.;  Homsi, M.;  Fishbein, M. C.;  Rubart, M.;  Lin, S. F.;  Xiao, D.;  Chen, H.;  Chen, P. S.;  Shou, W.; Li, B. Y., Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12. Am J Physiol Heart Circ Physiol 2019, 316 (2), H371-h379.

    22. Peng, J. L.;  Techasatian, W.;  Hato, T.; Liangpunsakul, S., Role of endotoxemia in causing renal dysfunction in cirrhosis. J Investig Med 2020, 68 (1), 26-29.

    23. Pianca, N.;  Di Bona, A.;  Lazzeri, E.;  Costantini, I.;  Franzoso, M.;  Prando, V.;  Armani, A.;  Rizzo, S.;  Fedrigo, M.;  Angelini, A.;  Basso, C.;  Pavone, F. S.;  Rubart, M.;  Sacconi, L.;  Zaglia, T.; Mongillo, M., Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery. J Physiol 2019, 597 (14), 3639-3656.

    24. Reissaus, C. A.;  Pineros, A. R.;  Twigg, A. N.;  Orr, K. S.;  Conteh, A. M.;  Martinez, M. M.;  Kamocka, M. M.;  Day, R. N.;  Tersey, S. A.;  Mirmira, R. G.;  Dunn, K. W.; Linnemann, A. K., A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo. Sci Rep 2019, 9 (1), 8449.

    25. Samanta, D.;  Clemente, T. M.;  Schuler, B. E.; Gilk, S. D., Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growth. PLoS Pathog 2019, 15 (12), e1007855.

    26. Sandoval, R. M.;  Molitoris, B. A.; Palygin, O., Fluorescent Imaging and Microscopy for Dynamic Processes in Rats. Methods Mol Biol 2019, 2018, 151-175.

    27. Shim, J. W.;  Territo, P. R.;  Simpson, S.;  Watson, J. C.;  Jiang, L.;  Riley, A. A.;  McCarthy, B.;  Persohn, S.;  Fulkerson, D.; Blazer-Yost, B. L., Hydrocephalus in a rat model of Meckel Gruber syndrome with a TMEM67 mutation. Scientific reports 2019, 9 (1), 1069.

    28. Singh, K.;  Sinha, M.;  Pal, D.;  Tabasum, S.;  Gnyawali, S. C.;  Khona, D.;  Sarkar, S.;  Mohanty, S. K.;  Soto-Gonzalez, F.;  Khanna, S.;  Roy, S.; Sen, C. K., Cutaneous Epithelial to Mesenchymal Transition Activator ZEB1 Regulates Wound Angiogenesis and Closure in a Glycemic Status-Dependent Manner. Diabetes 2019, 68 (11), 2175-2190.

    29. Tang, P. C.;  Alex, A. L.;  Nie, J.;  Lee, J.;  Roth, A. A.;  Booth, K. T.;  Koehler, K. R.;  Hashino, E.; Nelson, R. F., Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids. Stem Cell Reports 2019, 13 (1), 147-162.

    30. Tavakoli, M.;  Tsekouras, K.;  Day, R.;  Dunn, K. W.; Presse, S., Quantitative Kinetic Models from Intravital Microscopy: A Case Study Using Hepatic Transport. J Phys Chem B 2019, 123 (34), 7302-7312.

    31. Uchida, M.;  Maier, B.;  Waghwani, H. K.;  Selivanovitch, E.;  Pay, S. L.;  Avera, J.;  Yun, E.;  Sandoval, R. M.;  Molitoris, B. A.;  Zollman, A.;  Douglas, T.; Hato, T., The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration. J Clin Invest 2019, 129 (9), 3941-3951.

    32. VanderWall, K. B.;  Vij, R.;  Ohlemacher, S. K.;  Sridhar, A.;  Fligor, C. M.;  Feder, E. M.;  Edler, M. C.;  Baucum, A. J., 2nd;  Cummins, T. R.; Meyer, J. S., Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells. Stem cell reports 2019, 12 (2), 201-212.

    33. Vincentz, J. W.;  Firulli, B. A.;  Toolan, K. P.;  Arking, D. E.;  Sotoodehnia, N.;  Wan, J.;  Chen, P. S.;  de Gier-de Vries, C.;  Christoffels, V. M.;  Rubart-von der Lohe, M.; Firulli, A. B., Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. Circ Res 2019, 125 (6), 575-589.

    34. Vliet-Gregg, P. A.;  Robinson, K. L.;  Levan, J.;  Matsumoto, L. R.; Katzenellenbogen, R. A., NFX1-123 is highly expressed in cervical cancer and increases growth and telomerase activity in HPV 16E6 expressing cells. Cancer Lett 2019, 449, 106-113.

    35. Xu, J.;  Liu, Y.;  Li, Y.;  Wang, H.;  Stewart, S.;  Van der Jeught, K.;  Agarwal, P.;  Zhang, Y.;  Liu, S.;  Zhao, G.;  Wan, J.;  Lu, X.; He, X., Precise targeting of POLR2A as a therapeutic strategy for human triple negative breast cancer. Nat Nanotechnol 2019, 14 (4), 388-397.

    36. Yamamoto, W. R.;  Bone, R. N.;  Sohn, P.;  Syed, F.;  Reissaus, C. A.;  Mosley, A. L.;  Wijeratne, A. B.;  True, J. D.;  Tong, X.;  Kono, T.; Evans-Molina, C., Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic beta cell. The Journal of biological chemistry 2019, 294 (1), 168-181.

    37. Zhang, W.;  Yang, Y.;  Dong, Z.;  Shi, Z.; Zhang, J. T., Single-nucleotide polymorphisms in a short basic motif in the ABC transporter ABCG2 disable its trafficking out of endoplasmic reticulum and reduce cell resistance to anticancer drugs. J Biol Chem 2019, 294 (52), 20222-20232.

    38. Zhang, Y.;  Hato, T.;  Dagher, P. C.;  Nichols, E. L.;  Smith, C. J.;  Dunn, K. W.; Howard, S. S., Automatic segmentation of intravital fluorescence microscopy images by K-means clustering of FLIM phasors. Opt Lett 2019, 44 (16), 3928-3931.

    39. Zhou, T.;  Kyritsi, K.;  Wu, N.;  Francis, H.;  Yang, Z.;  Chen, L.;  O'Brien, A.;  Kennedy, L.;  Ceci, L.;  Meadows, V.;  Kusumanchi, P.;  Wu, C.;  Baiocchi, L.;  Skill, N. J.;  Saxena, R.;  Sybenga, A.;  Xie, L.;  Liangpunsakul, S.;  Meng, F.;  Alpini, G.; Glaser, S., Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2(-/-) mouse model of primary sclerosing cholangitis (PSC). EBioMedicine 2019, 48, 130-142

  • 2018
    1. Aref, M. W.;  Swallow, E. A.;  Chen, N. X.;  Moe, S. M.; Allen, M. R., Skeletal vascular perfusion is altered in chronic kidney disease. Bone reports 2018, 8, 215-220. 

    2. Avin, K. G.;  Vallejo, J. A.;  Chen, N. X.;  Wang, K.;  Touchberry, C. D.;  Brotto, M.;  Dallas, S. L.;  Moe, S. M.; Wacker, M. J., Fibroblast growth factor 23 does not directly influence skeletal muscle cell proliferation and differentiation or ex vivo muscle contractility. American journal of physiology. Endocrinology and metabolism 2018, 315 (4), E594-e604. 

    3. Basile, D. P.;  Collett, J. A.; Yoder, M. C., Endothelial colony-forming cells and pro-angiogenic cells: clarifying definitions and their potential role in mitigating acute kidney injury. Acta physiologica (Oxford, England) 2018, 222 (2).

    4. Basile, D. P.; Yoder, M. C., Unique Gene Expression in Developing Ascending Vasa Recta: A Tale of Tie. Journal of the American Society of Nephrology : JASN 2018, 29 (4), 1073-1074. 

    5. Bellchambers, H. M.; Ware, S. M., ZIC3 in Heterotaxy. Advances in experimental medicine and biology 2018, 1046, 301-327. 

    6. Brandt, S. L.;  Klopfenstein, N.;  Wang, S.;  Winfree, S.;  McCarthy, B. P.;  Territo, P. R.;  Miller, L.; Serezani, C. H., Macrophage-derived LTB4 promotes abscess formation and clearance of Staphylococcus aureus skin infection in mice. PLoS pathogens 2018, 14 (8), e1007244. 

    7. Brandt, S. L.;  Wang, S.;  Dejani, N. N.;  Klopfenstein, N.;  Winfree, S.;  Filgueiras, L.;  McCarthy, B. P.;  Territo, P. R.; Serezani, C. H., Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice. JCI insight 2018, 3 (17). 

    8. Casasnovas, J. J.;  Jo, Y.;  Rao, X.;  Xuei, X.;  Brown, M. E.; Kua, K. L., High Glucose Alters Fetal Rat Islet Transcriptome and Induces Progeny Islet Dysfunction. The Journal of endocrinology 2018. 

    9. Chen, N. X.;  O'Neill, K. D.; Moe, S. M., Matrix vesicles induce calcification of recipient vascular smooth muscle cells through multiple signaling pathways. Kidney international 2018, 93 (2), 343-354. 

    10. Clendenon, S. G.;  Fu, X.;  Von Hoene, R. A.;  Clendenon, J. L.;  Sluka, J. P.;  Winfree, S.;  Mang, H.;  Martinez, M.;  Filson, A. J.;  Klaunig, J. E.;  Glazier, J. A.; Dunn, K. W., A simple automated method for continuous fieldwise measurement of microvascular hemodynamics. Microvascular research 2019, 123, 7-13. 

    11. Dominguez, J. M., 2nd;  Dominguez, J. H.;  Xie, D.; Kelly, K. J., Human extracellular microvesicles from renal tubules reverse kidney ischemia-reperfusion injury in rats. PloS one 2018, 13 (8), e0202550. 

    12. Drucker, N. A.;  Jensen, A. R.;  Te Winkel, J. P.;  Ferkowicz, M. J.; Markel, T. A., Loss of endothelial nitric oxide synthase exacerbates intestinal and lung injury in experimental necrotizing enterocolitis. Journal of pediatric surgery 2018, 53 (6), 1208-1214. 

    13. Dunn, K. W.;  Sutton, T. A.; Sandoval, R. M., Live-Animal Imaging of Renal Function by Multiphoton Microscopy. Current protocols in cytometry 2018, 83, 12.9.1-12.9.25. 

    14. Eadon, M. T.;  Cheng, Y. H.;  Hato, T.;  Benson, E. A.;  Ipe, J.;  Collins, K. S.;  De Luca, T.;  El-Achkar, T. M.;  Bacallao, R. L.;  Skaar, T. C.; Dagher, P. C., In Vivo siRNA Delivery and Rebound of Renal LRP2 in Mice. J Drug Deliv 2017, 2017, 4070793. 

    15. Fligor, C. M.;  Langer, K. B.;  Sridhar, A.;  Ren, Y.;  Shields, P. K.;  Edler, M. C.;  Ohlemacher, S. K.;  Sluch, V. M.;  Zack, D. J.;  Zhang, C.;  Suter, D. M.; Meyer, J. S., Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells. Scientific reports 2018, 8 (1), 14520. 

    16. Fu, X.;  Sluka, J. P.;  Clendenon, S. G.;  Dunn, K. W.;  Wang, Z.;  Klaunig, J. E.; Glazier, J. A., Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models. PloS one 2018, 13 (9), e0198060. 

    17. Gadgil, N. J.;  Salama, P.;  Dunn, K. W.; Delp, E. J., Segmentation of biological images containing multitarget labeling using the jelly filling framework. Journal of medical imaging (Bellingham, Wash.) 2018, 5 (4), 044006. 

    18. Garrett, J.;  Sampson, C. H.;  Plett, P. A.;  Crisler, R.;  Parker, J.;  Venezia, R.;  Chua, H. L.;  Hickman, D. L.;  Booth, C.;  MacVittie, T.;  Orschell, C. M.; Dynlacht, J. R., Characterization and Etiology of Swollen Muzzles in Irradiated Mice. Radiation research 2019, 191 (1), 31-42.

    19. Go, E.;  Tarnawsky, S. P.;  Shelley, W. C.;  Banno, K.;  Lin, Y.;  Gil, C. H.;  Blue, E. K.;  Haneline, L. S.;  O'Neil, K. M.; Yoder, M. C., Mycophenolic acid induces senescence of vascular precursor cells. PloS one 2018, 13 (3), e0193749. 

    20. Hato, T.;  Maier, B.;  Syed, F.;  Myslinski, J.;  Zollman, A.;  Plotkin, Z.;  Eadon, M. T.; Dagher, P. C., Bacterial sepsis triggers an antiviral response that causes translation shutdown. J Clin Invest 2019, 129 (1), 296-309. 

    21. Hato, T.;  Winfree, S.; Dagher, P. C., Kidney Imaging: Intravital Microscopy. Methods in molecular biology (Clifton, N.J.) 2018, 1763, 129-136. 

    22. Hato, T.;  Zollman, A.;  Plotkin, Z.;  El-Achkar, T. M.;  Maier, B. F.;  Pay, S. L.;  Dube, S.;  Cabral, P.;  Yoshimoto, M.;  McClintick, J.; Dagher, P. C., Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney. Journal of the American Society of Nephrology : JASN 2018, 29 (1), 104-117. 

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