Physician-scientists at IU School of Medicine conduct ground-breaking liver research to understand primary sclerosing cholangitis.
Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a condition that affects the bile ducts. These ducts carry bile from the liver, where bile is produced, to the gallbladder, where it is stored, and to the small intestine, where it aids in digestion. Primary sclerosing cholangitis occurs because of inflammation in the bile ducts (cholangitis) that leads to scarring (sclerosis) and narrowing of the ducts. As a result, bile cannot be released to the gallbladder and small intestine, and it builds up in the liver.