Research in the Department of Neurology focuses on Alzheimer’s disease, epilepsy, movement disorders, pediatric neurology, stroke and more.

Neurology Research

Built on a long tradition of work in cerebrovascular disease, the department's preclinical and clinical neurologic research programs are dynamic, multidisciplinary groups focused on improved prevention and treatment.

a researcher uses a pipette in the lab

The Department of Neurology at Indiana School of Medicine has made great strides in transforming patient lives through comprehensive research. The department is home to the nation’s most comprehensive study of early-onset Alzheimer’s disease as well as innovative investigations in a wide array of therapeutic areas supported by federal grants from the National Institute of Neurological Disorders and Stroke (NINDS), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Aging (NIA), and the National Science Foundation. Faculty in this department have an extensive track record of successfully partnering with other academic medical centers throughout the United States and the pharmaceutical industry to test and refine new treatments.

Participate in Research

Want to help researchers find new ways to diagnose and treat neurologic conditions? Contact the Neurology Clinical Trials team to get connected to ongoing studies in Indiana.

120
publications
$13.7
million in grant funding
69
clinical trials
research programs
close up of lab bench equipment

Indiana Alcohol Research Center

The Indiana Alcohol Research Center is a specialized center where experts study behavioral, genetic and central nervous system factors that contribute to alcohol-use disorders.

a clinician meets with a clinical trials participant

LEADS

The Longitudinal Early-onset AD Study (LEADS) is funded by the National Institute on Aging to address several major gaps in Alzheimer’s disease and related dementias research.

a clinician meets with a clinical trial participant

Neurology Clinical Trials

The Department of Neurology clinical trials program specialists help connect participants and their families with the support needed to improve both their health and quality of life.

faculty labs
liana apostolova and colleague review results on a computer monitor

Apostolova Lab

The Apostolova lab focuses on early-onset Alzheimer’s disease and the development and validation of imaging and genetics biomarkers. 

Jeffrey Dage lab

Dage Lab

The Dage Lab is focused on the discovery and development of biomarkers to aid in the understanding of neurodegenerative diseases.

a lab group poses for a photo

Kareken Lab

The Kareken Lab uses neuroimaging to understand the human brain’s reward system in studies of alcoholism and obesity.

an EEG readout

Obeid Lab

The Obeid lab studies the mechanisms of seizures and the accompanying cognitive and behavioral deficits using electrophysiological, behavioral and molecular techniques.

research image under microscope

Wilcock Lab

The Wilcock lab was established in 2011 with a focus on vascular contributions to cognitive impairment and dementia (VCID) and neuroinflammation in VCID and Alzheimer’s disease.

Researchers
6815-Apostolova, Liana Liana G. Apostolova, MD, MS

Liana G. Apostolova, MD, MS

Associate Dean of Alzheimer's Disease Research

13103-Brosch, Jared Jared R. Brosch, MD

Jared R. Brosch, MD

Associate Professor of Clinical Neurology

42105-Clark, David David G. Clark, MD

David G. Clark, MD

Associate Professor of Clinical Neurology

60676-Dage, Jeff Jeff Dage, PhD

Jeff Dage, PhD

Senior Research Professor of Neurology

15003-Du, Yansheng Yansheng Du, PhD

Yansheng Du, PhD

Professor of Neurology

2744-Dzemidzic, Mario Mario Dzemidzic, PhD

Mario Dzemidzic, PhD

Associate Research Professor of Neurology

19912-Gu, Huiying Huiying Gu, M.D.

Huiying Gu, M.D.

Assistant Research Professor of Neurology

59893-Hammers, Dustin Dustin Hammers, PhD

Dustin Hammers, PhD

Associate Professor of Neurology

Faculty Profile Placeholder IUSM Logo Valerie L. Joers, PhD

Valerie L. Joers, PhD

Associate Research Professor of Neurology

1901-Kareken, David David A. Kareken, PhD

David A. Kareken, PhD

Professor of Neurology

62996-Khan, Naazneen Naazneen Khan, PhD

Naazneen Khan, PhD

Assistant Research Professor of Neurology

4985-Kosobud, Ann Ann E. Kosobud, PhD

Ann E. Kosobud, PhD

Associate Research Professor of Neurology

Faculty Profile Placeholder IUSM Logo Kelly B. Menees, PhD

Kelly B. Menees, PhD

Assistant Research Professor of Neurology

Faculty Profile Placeholder IUSM Logo Andrea R. Merchak, PhD

Andrea R. Merchak, PhD

Assistant Research Professor of Neurology

62378-Obeid, Makram Makram Obeid, MD

Makram Obeid, MD

Assistant Professor of Neurology

Faculty Profile Placeholder IUSM Logo Malu G. Tansey, PhD

Malu G. Tansey, PhD

James A. Caplin, M.D. Professor of Alzheimer's Research

64139-Weekman, Erica Erica M. Weekman, PhD

Erica M. Weekman, PhD

Assistant Research Professor of Neurology

63805-Wilcock, Donna Donna M. Wilcock, PhD

Donna M. Wilcock, PhD

Barbara and Larry Sharpf Professor of Alzheimer's Disease Research

10669-Williams, Linda Linda S. Williams, MD

Linda S. Williams, MD

Professor of Neurology

44720-Yu, Meichen Meichen Yu, PhD

Meichen Yu, PhD

Assistant Professor of Radiology & Imaging Sciences