Showing results for Research Findings

a close up photo of gloved hands preparing a sample in the lab

IU researchers identify new gene mutation that alters Alzheimer’s disease risk

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

IU School of Medicine | Sep 06, 2023

Study: health equity an important aspect of improving quality of care provided to children in emergency departments

A new multi-site study led by Indiana University School of Medicine found increasing pediatric readiness in emergency departments reduces, but does not eliminate, racial and ethnic disparities in children and adolescents with acute medical emergencies.

IU School of Medicine | Sep 05, 2023

Overlooked part of brain could play critical role in addiction recovery

Researchers from Indiana University School of Medicine have discovered a neglected brain region that could play a critical role in how likely a person with drug use disorders is to relapse, even after a long withdrawal period. Their findings were published recently in Biological Psychiatry.

IU School of Medicine | Aug 24, 2023

Tau protein in Alzheimer's disease, illustration. The insets show two ways in which pathological phosphorylation (yellow) of Tau proteins (red-orange) by kinases (blue-purple) affect nerve cells in what is called a neurofibrillary tangle. The main illustration showing a nerve cell (neuron, blue, lower left) and its axon (across bottom), shown in a misshapen and abnormal state. Pathological aggregations of tau proteins cause disintegration of microtubules (inset at left). The transport of synaptic vesicles (orange-blue spheres, inset at right) is also interrupted. A neurofibrillary tangle consists of abnormal aggregates and insoluble fibres of the protein tau. Tau protein is an abundant neural protein, aggregations of which are thought to play a role in Alzheimer's disease and other neural disorders.

Neuroscientists create new resource to improve Alzheimer’s disease research models

Genetic diversity key to new study on abnormal protein accumulation in the brain—a hallmark of Alzheimer’s disease development

IU School of Medicine | Aug 22, 2023

Mila, a six-year-old orangutan born at the Indianapolis Zoo.

IU researchers diagnose Indianapolis Zoo orangutan with rare genetic disease

Researchers from Indiana University School of Medicine have diagnosed a Sumatran Orangutan at the Indianapolis Zoo with a rare genetic disease called Alkaptonuria.

IU School of Medicine | Jul 27, 2023

Michael Ferkowicz, PhD, MS, examines images of human kidney cells.

Nephrology researchers create cellular map of human kidney, showing tissue in unprecedented detail

Indiana University School of Medicine researchers have helped shed important light on the cellular makeup of the human kidney in both healthy and diseased states—findings that could help scientists identify new targets for early detection of and better treatments for kidney disease.

IU School of Medicine | Jul 26, 2023

a toddler plays with toys in the early autism evaluation hub

IU-developed statewide initiative shows primary care clinicians can diagnose autism in young children with high accuracy

A new study led by Indiana University School of Medicine researchers shows primary care clinicians who receive specialized training can make accurate autism diagnoses for over 80 percent of young children referred with developmental delays, providing compelling evidence that community-based models of autism evaluation are a potential solution for improving access to this needed service.

IU School of Medicine | Jul 18, 2023

Cristian Lasagna-Reeves, PhD presents at AAIC 2023.

IU School of Medicine researchers share expertise at international Alzheimer’s disease conference

Researchers from Indiana University School of Medicine will have a large presence and leadership role at the upcoming Alzheimer’s Association International Conference 2023 in Amsterdam, Netherlands, with involvement in more than 150 presentations at the four-day meeting.

IU School of Medicine | Jul 17, 2023

Researchers discover group of genes that influence pain and brain communication can also influence alcohol use disorder risk

An estimated 16 million people in the United States have alcohol use disorders (AUDs), according to the National Institutes on Alcohol Abuse and Alcoholism (NIAAA).

IU School of Medicine | Jul 13, 2023

Researcher applies a wound dressing to a man's foot.

Defective closure of diabetic foot ulcers is associated with higher risk of wound recurrence

Results from a new study of diabetic foot ulcers and the risk of wound recurrence can help health care workers measure the likelihood that the wound will reopen in the future. These findings are likely to lead to further studies aimed at decreasing amputation rates for the tens of millions of people with diabetes in the United States.

IU School of Medicine | Jun 26, 2023