Research Programs

Research programs within the IU Simon Comprehensive Cancer Center range from exploring the molecular changes that cause cancer to developing targeted therapies to prevent and treat cancer.

Since its founding, researchers at the center have made protocol-defining discoveries that have changed the way doctors treat breast cancer; gastrointestinal cancer, including pancreatic and colon cancers; genitourinary cancer, such as germ cell tumors, bladder and prostate cancer; hematologic disorders, including multiple myeloma and leukemia; thoracic cancer; thymoma; and thymic carcinoma. The center’s  bone marrow and stem cell transplantation programs also are internationally recognized.

Tumor Microenvironment and Metastasis

The Tumor Microenvironment and Metastasis program’s discoveries lead to clinical trials in collaboration with other IU Simon Comprehensive Cancer Center research programs.

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Cancer Prevention and Control

The Cancer Prevention and Control (CPC) research program focuses on cancer risk reduction and early detection as well as survivorship and symptom science.

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Experimental and Developmental Therapeutics

Research focused on experimental and developmental therapeutics seeks to develop mechanism-based therapy for human cancer.

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Hematopoiesis and Hematologic Malignancies

Researchers in this program focus on enhancing treatment of hematologic malignancies, with a focus on leukemia, pre-leukemia and multiple myeloma.

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