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Clinical Trial Opportunities

Investigators at the Center for Diabetes and Metabolic Diseases conduct a number a clinical trials focused on the prevention and treatment of Type 1 diabetes, Type 2 diabetes and obesity.

  • TrialNet

    TrialNet, the largest international network of Type 1 diabetes researchers, has a clinical center based at Riley Hospital for Children.


    The Rare and Atypical Diabetes Network (RADIANT) aims to discover and define rare and atypical forms of diabetes. These refined diagnoses will be used by diabetes researchers, physicians, and patients to accurately explain their disease. The study entails genetic and clinical testing for enrolled participants.

    Rare and Atypical Diabetes Network logoPI: Carmella Evans-Molina, MD, PhD

    For more information, please contact study coordinator Kelly Moors at

  • RISE Adult Medication Study
    The RISE Adult Medication Study is a clinical trial in adults with prediabetes and early Type 2 diabetes that conducts testing on whether lowering glucose levels will lead to the recovery of the pancreatic beta-cell function.
  • GRADE Study
    The GRADE Study clinical trial compares commonly used diabetes medications combined with metformin for effectiveness in lowering blood sugar and improving patient-centered outcomes.
Find more information related to clinical trials in pediatric diabetes on the Pediatric Diabetes Clinical Research page.

A complete list of all diabetes clinical trials being conducted at IU School of Medicine can be found on the Indiana Clinical and Translational Sciences Institute (CTSI) website. 

Why participate in clinical trials?

Find more information about the benefits of participating in clinical trials.

Participation Info