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Faculty experts at Indiana University School of Medicine Department of Urology are researching new ways to diagnose and treat benign prostatic hyperplasia (BPH), or enlarged prostate.


Researchers are comparing the outcomes of patients who receive room temperature fluid during holmium laser enucleation of the prostate (HoLEP) to those who receive warmed fluid during HoLEP. They are attempting to determine if keeping patients warmer during surgery shortens recovery time. HoLEP is a minimally invasive surgery for an enlarged prostate. Patients scheduled to undergo HoLEP with a prostate size estimated greater than 100 grams may be eligible to participate.

Moses Laser System for HoLEP

Researchers are comparing bleeding complications and recovery time between men undergoing HoLEP with a standard laser system compared to a new laser system called Moses. The Moses laser system uses a sequential fire laser technology that results in more efficient energy delivery to the tissue without increasing heat delivery. All patients undergoing HoLEP are eligible for this study.

Laser Prostatectomy Database and Registry

Researchers are studying the long-term outcomes of using laser prostatectomy techniques for BPH treatment. The goal is to document these outcomes to study the degree of voiding improvement achievable by these new techniques, the durability of outcomes and the safety of these procedures. Researchers will review the outcomes by creating a database and registry of patients with BPH who undergo laser prostatectomy.

Clinical Trial Details